Transparency data

Aggregate net sales and payment information: May 2025

Published 11 July 2025

Measured sales as of May 2025

Table 1A: measured sales reported under the 2019 voluntary scheme

Period 2019 voluntary scheme (£million) Statutory scheme (£million) Parallel imports (£million) Total (£million)
2023 (annual) 12,545 658 704 13,908

Table 1B: measured sales reported under the 2024 voluntary scheme for quarter 1 2024 (January to March 2024)

Period 2024 voluntary scheme (£million) Statutory scheme (£million) Parallel imports (£million) Total (£million)
Jan to Mar 2024 (quarter 1) 3,347 64 167 3,579

Table 1C: measured sales reported under the 2024 voluntary scheme for quarter 2 to quarter 4 2024 (April to December 2024)

Period 2024 voluntary scheme: newer presentations (£million) 2024 voluntary scheme: older presentations (£million) Statutory scheme (£million) Parallel imports (£million) Total (£million)
Apr to Jun 2024 (quarter 2) 2,184 1,275 62 161 3,681
Jul to Sep 2024 (quarter 3) 2,370 1,310 58 173 3,911
Oct to Dec 2024 (quarter 4) 2,254 1,369 56 180 3,859

Table 1D: measured sales reported under the 2024 voluntary scheme for January to March 2025 onwards

Period 2024 voluntary scheme: newer presentations (£million) 2024 voluntary scheme: older presentations (£million) Statutory scheme: newer presentations (£million) Statutory scheme: older presentations (£million) Parallel imports (£million) Total (£million)
Jan to Mar 2025 (quarter 1) 2,107 1,260 6 51 179 3,604

Tables 1A, 1B, 1C and 1D notes:

1. Tables 1A, 1B, 1C and 1D set out aggregate information to date for calendar years 2023, 2024 and 2025 about measured sales subject to the affordability mechanism. They include information received on parallel imports from IQVIA adjusted to net prices, and information from audited annual sales reports and unaudited quarterly sales reports provided by members of the 2019 and 2024 voluntary schemes and the statutory scheme.

2. The baseline for measured sales in respect of the 2024 voluntary scheme, statutory scheme and parallel imports has been calculated in accordance with annex 4 of the 2024 voluntary scheme.

3. ‘Measured sales’ is defined in the glossary of the 2024 voluntary scheme for branded medicines pricing, access and growth (VPAG) as “sales of scheme products by scheme members, statutory scheme sales and parallel import sales, but excluding exemptions from measured sales”.

4. Annual figures for the 2024 voluntary scheme and the statutory scheme reflect any audited sales reports received.

5. Measured sales in any particular period reflects all relevant scheme members in either the 2024 voluntary scheme or statutory scheme during that period. For example, if a company moves from the statutory scheme to the voluntary scheme at the start of a calendar year, that company’s measured sales will appear under the statutory scheme in the year it was covered by the regulations but the voluntary scheme in the year it joined VPAG.

6. For VPAG, quarter 1 2024 was a transition period, and therefore the data for this quarter was provided at the aggregate level only. For the statutory scheme, the affordability mechanism was not split by newer and older medicines in quarter 2 to quarter 4 2024, and therefore the data for this period was provided at the aggregate level only.

2024 voluntary scheme - eligible sales, resulting total scheme payments and payment element relating to VPAG investment programme

Table 2A: 2024 voluntary scheme - eligible sales, total resulting total scheme payments, excluding the annual older medicines top-up payments, and payment element relating to VPAG investment programme

Period Aggregate eligible sales (£million) Resulting aggregate scheme payments, excluding annual older medicines top-up payments (£million) Element of aggregate scheme payment relating to VPAG investment programme (£million)
Jan to Mar 2024 3,050 595 1
Apr to Jun 2024 3,264 430 1
Jul to Sep 2024 3,511 464 1
Oct to Dec 2024 3,442 450 1
Jan to Mar 2025 2,967 536 18

Table 2B: 2024 voluntary scheme - eligible sales of newer medicines and resulting scheme payments

Period Aggregate eligible sales: newer medicines (£million) Resulting aggregate scheme payments: newer medicines (£million)
Apr to Jun 2024 2,040 308
Jul to Sep 2024 2,219 335
Oct to Dec 2024 2,082 314
Jan to Mar 2025 1,852 424

Table 2C: 2024 voluntary scheme - eligible sales for older medicines and resulting scheme payments, excluding annual top-up payments

Period Aggregate eligible sales: older medicines (£million) Resulting aggregate scheme payments: older medicines, excluding annual top-up payments (£million)
Apr to Jun 2024 1,224 122
Jul to Sep 2024 1,291 129
Oct to Dec 2024 1,360 136
Jan to Mar 2025 1,114 111

Tables 2A, 2B and 2C notes:

1. Tables 2A, 2B and 2C, which are derived from unaudited quarterly sales reports and any audited annual sales reports received from members of the 2024 voluntary scheme, set out aggregate information showing eligible sales covered by the scheme payment and the resulting scheme payments. Table 2A also reports the element of the total aggregate payment relating to the VPAG investment programme.

2. ‘Eligible sales’ is defined in the glossary of the 2024 voluntary scheme as “sales of scheme products by scheme members but excluding exemptions from eligible sales”. The relevant percentage payments apply to these sales. Eligible sales exclude certain types of sales, including the first £6 million of sales by a medium-sized company and new active substance (NAS) sales. Both of these sales categories are, however, included in measured sales and therefore the calculation of the overall sum to be repaid across all scheme members.

3. Table 2B reports aggregate and resulting payments generated by the headline payment percentage for the relevant period. Table 2C reports aggregate eligible sales and resulting payments generated by the basic payment percentage for quarterly periods and the basic payment percentage plus the calculated top-up payment percentages for annual periods.

Statutory scheme - eligible sales and resulting payments

Table 3A: statutory scheme - eligible sales and resulting total scheme payments, excluding the annual older medicines top-up payments, 2023 onwards

Period Aggregate eligible sales (£million) Total statutory scheme payment (£million)
2023 (annual) 658 182
Jan to Mar 2024 63 14
Apr to Jun 2024 60 13
Jul to Sep 2024 58 13
Oct to Dec 2024 55 12
2024 (annual) 236 52
Jan to Mar 2025 57 6

Table 3B: statutory scheme - eligible sales of newer medicines and resulting scheme payments

Period Aggregate eligible sales: newer medicines (£million) Resulting aggregate scheme payments: newer medicines (£million)
Jan to Mar 2025 6 1

Table 3C: statutory scheme - eligible sales for older medicines and resulting scheme payments, excluding annual top-up payments

Period Aggregate eligible sales: older medicines (£million) Resulting aggregate scheme payments: older medicines, excluding annual top-up payments (£million)
Jan to Mar 2025 51 5

Tables 3A, 3B and 3C notes:

1. Tables 3A, 3B and 3C are derived from unaudited and audited statutory scheme sales reports. They set out aggregate information, showing eligible sales covered by the statutory scheme payment and the resulting payment.

2. The term ‘eligible sales’ was implemented in the statutory scheme from 2024 onwards. For 2023, eligible sales are equivalent to net sales.

General notes

1. The information in all tables is that held on the Department of Health and Social Care’s database at 22 to 23 May 2025.

2. Totals may not sum due to rounding.

3. All tables are subject to future correction such as where audited data replaces best available data and will be updated at each quarterly publication point to reflect the latest available information. The audit and reconciliation arrangements are set out in paragraphs 4.68 to 4.74 of the 2024 voluntary scheme. The statutory scheme audit requirements are set out at paragraph 23 of the regulations.

4. As set out in the scheme documentation, a 2-stage voluntary scheme-end reconciliation process to address any outstanding under or over payments will reflect the fact that final audited and de facto audited annual sales reports for 2027 and 2028 will not be received until 2029 and 2030, at the earliest, respectively. It will also account for any remaining rounding impact.

5. Following the close of the third quarter of 2029, the department should have received audited or de facto audited returns for measured sales made in 2027, and updated data for measured sales made in 2028. This may be a mix of audited returns for scheme members with a financial year end of December, and unaudited returns for scheme members whose financial year end date differs from the calendar year end, or who have been delayed in providing their audited returns. This data will be used to calculate a revised payment percentage and corresponding payment for 2028. The revised payment percentage will be calculated to 2 decimal places. Any change arising in the payment due from scheme members following the revision of the 2028 payment percentage will be payable (or refundable) in the first quarter of 2030. This process will repeat following receipt of audited and de facto audited returns for measured sales made in 2028 a year later.